Full publication list of Prof. Andreas A. Mueller

 

  1. Schönegg D, Deyhle H, Schulz G, Tanner C, Ahmed S, Atwood R, Mueller AA, Müller-Gerbl M, Mezey S, Lieber RL, Khounsary A, Müller B. Three-dimensional hard x-ray micro-tomographic imaging of the human palatal anatomy and gracilis muscle. Event: Optical Engineering + Applications, 2024, San Diego, California, United States. Proceedings Volume 13152, Developments in X-Ray Tomography XV; 1315229 (2024) https://doi.org/10.1117/12.3035601

  2. Schnabel TN, Lill Y, Benitez BK, Nalabothu P, Metzler P, Mueller AA, Gross M. Gözcü B, Solenthaler B. Large-Scale 3D Infant Face Model. In: Linguraru, M.G., et al. Medical Image Computing and Computer Assisted Intervention – MICCAI 2024. MICCAI 2024. Lecture Notes in Computer Science, vol 15003. Springer, Cham. https://doi.org/10.1007/978-3-031-72384-1_21,

  3. Santos JWM, Mueller AA, Benitez BK, Lill Y, Nalabothu P, Muniz FWMG. Smartphone-based scans of palate models of newborns with cleft lip and palate: Outlooks for three-dimensional image capturing and machine learning plate tool. Orthod Craniofac Res. 2024 Sep 22. doi: 10.1111/ocr.12859. Epub ahead of print. PMID: 39306752.

  4. Fell M, Breakey W, Benitez BK, Mueller AA, Chong DK. The Preservation Technique for Incomplete Unilateral Cleft Lip Reconstruction. Plast Reconstr Surg Glob Open. 2024 Sep 18;12(9):e6172. doi: 10.1097/GOX.0000000000006172. PMID: 39296618; PMCID: PMC11410330.

  5. de Macêdo Santos JW, Benitez BK, Baumhoer D, Schönegg D, Schrepfer T, Mueller AA, Thieringer FM. Intraosseous myofibroma mimicking an odontogenic lesion: case report, literature review, and differential diagnosis. World J Surg Onc 22, 246 (2024). https://doi.org/10.1186/s12957-024-03520-4

  6. Mueller AADas müssen Eltern über die Lippen-Kiefer-Gaumenspalte wissen. 2024 Schweizer Illustrierte. PDF version.
     
  7. Teuber Lobos C, Benitez BK, Lill Y, Kiser LE, Tache A, Fernandez-Pose M, Campolo Gonzalez A, Nalabothu P, Sharma N, Thieringer FM, Vargas Díaz A, Mueller AA. Cleft lip and palate surgery simulator: Open source simulation model, Heliyon, Volume 10, Issue 8, 2024, https://doi.org/10.1016/j.heliyon.2024.e29185.
     
  8. Benitez BK, Rasadurai A, Boccalatte L, Mueller AAPre-epiglottic baton plate in newborns with Pierre Robin sequence: revisiting the practical workflow. The Laryngoscope. 2024; 134: 4766-4769. https://doi.org/10.1002/lary.31508.
     
  9. Benitez BK, Brudnicki A, Tache A, Wieprzowski Ł, Surowiec Z, Nalabothu P, Lill Y, Mueller AA. Comparative study on cleft palate morphology after passive presurgical plate therapy in unilateral cleft lip and palate. Journal of Plastic, Reconstructive & Aesthetic Surgery, Volume 92, 2024 (198-206), https://doi.org/10.1016/j.bjps.2024.03.001
     
  10. Shahbazi A, Mueller AA, Mezey S, Gschwindt S, Kiss T., Bksa G, Kisnisci R. Is the collateral circulation pattern in the hard palate affected by cleft deformity? Clinical Oral Investigations. Volume 28, article number 277, 2024.
     
  11. Mezey S, Schönegg D, Benitez BK, Toranelli M, Hussain SA, Müller-Gerbl M, Mueller AA.
    Poster: New Insights into the anatomical basis of human cleft palate surgery. Facing Forward, Applied Craniofacial Anatomy: Evolution, Development & Bioengineering. Anatomical Society Winter Meeting, 3rd-5th January 2024.

  12. Eckstein-Halla N, Filippi C, Müller AA. Lippen-Kiefer-Gaumen-Spalten. In: Filippi A Filippi C Neuhaus KW Quintessenz Verlags-GmbH. Die Zahnmedizinische Behandlung Von Menschen Mit Special Needs. (Copyright owned by Quintessenz Verlag) 1. Auflage 2024 ed. Berlin: Quintessenz Verlag; 2024.
     
  13. Lill Y, Cespedes WV, Benitez BK, Eckstein-Halla NC, Leitmeyer KS, Gürtler N, Stieger C, Mueller AA, Screening for congenital hearing impairment with brainstem evoked response audiometry in isolated orofacial cleft, International Journal of Oral and Maxillofacial Surgery2024; 53 (5) 376-381https://doi.org/10.1016/j.ijom.2023.11.008
     
  14. Lingens L, Gözcü B, Schnabel T, Lill Y, Benitez BK, Nalabothu P, Mueller AA, Gross M. and Solenthaler B. Image-Based 3D Reconstruction of Cleft Lip and Palate Using a Learned Shape Prior. In International Workshop on Applications of Medical AI (pp. 94-103). 2023 Cham: Springer Nature Switzerland. https://people.inf.ethz.ch/~sobarbar/paper/Lingens23.pdf
     
  15. Meyer S, Benitez BK, Thieringer FM, Mueller AA. 3D-printable Open-source Cleft Lip and Palate Impression Trays – A Single-Impression-Workflow. Plastic and Reconstructive Surgery, May 15, 2023.  DOI: 10.1097/PRS.0000000000010684 
     
  16. Schnabel TN, Gözcü B, Gotardo P, Lingens L, Dorda D, Vetterli F, Emhemmed A, Nalabothu P, Lill Y, Benitez BK, Mueller AA, Gross M, Solenthaler B. Automated and data-driven plate computation for presurgical cleft lip and palate treatment. Int J Comput Assist Radiol Surg. 2023 Apr 2. doi: 10.1007/s11548-023-02858-6
     
  17. Benitez BK, Brudnicki A, Surowiec Z, Wieprzowski L, Rasadurai A, Nalabothu P, Lill Y, Mueller AA. Digital Impressions from Newborns to Preschoolers with Cleft Lip and Palate: A Two-Centers Experience, Journal of Plastic,Reconstructive & Aesthetic Surgery. 2022.
    https://doi.org/10.1016/j.bjps.2022.08.015
     
  18. Zarean P, Zarean P, Thieringer FM, Mueller AA, Kressmann S, Erismann M, Sharma N, Benitez BK. A Point-of-Care Digital Workflow for 3D Printed Passive Presurgical Orthopedic Plates in Cleft Care. Children. 2022; 9(8):1261. https://doi.org/10.3390/children9081261
     
  19. Benitez BK, Weibel SK, Halbeisen FS, Lill Y, Nalabothu P, Tache A, Mueller AA. Craniofacial Growth at Age 6–11 Years after One-Stage Cleft Lip and Palate Repair: A Retrospective Comparative Study with Historical Controls. Children. 2022; 9(8):1228. https://doi.org/10.3390/children9081228
     
  20. Reinhold A, Meyer P, Bruder E, Soleman J, von der Weid N, Mueller AA, Savic M, Congenital orbital teratoma: A clinicopathologic case report. American Journal of Ophthalmology Case Reports, 2022; 26, https://doi.org/10.1016/j.ajoc.2022.101420.
     
  21. Benitez BK, Brudnicki A, Surowiec Z, Singh RK, Nalabothu P, Schumann D, Mueller AA, Continuous Circular Closure in Unilateral Cleft Lip and Plate Repair in One Surgery, Journal of Cranio-Maxillofacial Surgery, 2022; 50(1). https://www.sciencedirect.com/science/article/pii/S1010518221001839
     
  22. Benitez B, Brudnicki A, Nalabothu P, von Jackowski J, Bruder E, Mueller AA. Histologic aspect of the curved vomerine mucosa in cleft lip and palate. The Cleft Palate-Craniofacial Journal 2021; Volume 59, Issue 8. https://doi.org/10.1177/10556656211031419
     
  23. Ureel M, Augello M, Holzinger D, Wilken T, Berg BI, Zeilhofer HF, Millesi G, Juergens P, Mueller AA. Cold Ablation Robot-Guided Laser Osteotome (CARLO®): From Bench to Bedside. J. Clin. Med. 2021; 10(3):450. https://doi.org/10.3390/jcm10030450 
     
  24. Holzinger D, Ureel M, Wilken T, Mueller AA, Schicho K, Milles G, Juergens P. First-in-man application of a cold ablation robot guided laser osteotome in midface osteotomies. J Cranio-Maxillofac Surg. Volume 49, Issue 7, July 2021, Pages 531-537. 
    https://doi.org/10.1016/j.jcms.2021.01.007
     
  25. Mueller AA. Weniger Chirurgie und mehr Biologie. Der kombinierte Lippen- und Gaumenverschluss in einer Operation zugunsten der Gewebeschonung. In: Textspalte Nr. 31 / 2020. Vereinigung der Eltern von Spaltkindern Schweiz.
  26. Mueller AACleft-Q Patient reported outcome measure for clefts translation for German (Switzerland) 2022. Accredidated and License by McMaster University, Toronto.

  27. Weibel Seraina. Schädelwachstum nach frühem Komplettverschluss einseitiger Lippen-, Kiefer- Gaumen- Segelspalten in einer Operation mittels Stiellappen nach Veau. 2020. Doctorate Dental Medicine, University of Basel. Supervised-student-publication by Mueller AAhttps://edoc.unibas.ch/81217/
     
  28. Nalabothu P, Verna C, Benitez BK, Dalstra M, Mueller AA. Load Transfer during Magnetic Mucoperiosteal Distraction in Newborns with Complete Unilateral and Bilateral Orofacial Clefts: A Three-Dimensional Finite Element Analysis. Appl. Sci. 2020;10(21):7728. https://doi.org/10.3390/app10217728
     
  29. Nalabothu P, Verna C, Steineck M, Mueller AA, Dalstra M. The biomechanical evaluation of magnetic forces to drive osteogenesis in newborn’s with cleft lip and palate. J Mater Sci: Mater Med 2020;31:79. doi.org/10.1007/s10856-020-06421-6
     
  30. Nalabothu P, Benitez BK, Dalstra M, Verna C, Mueller AA. Three-Dimensional Morphological Changes of the True Cleft under Passive Presurgical Orthopaedics in Unilateral Cleft Lip and Palate: A Retrospective Cohort Study. J Clin Med. 2020;9(4):962. doi.org/10.3390/jcm9040962
     
  31. Can Esad. Erstellung eines digitalen Diagnoseregisters und Erfassung der dreidimensionalen Ausgangsbefunde für die elektronische Patientenakte bei Lippen-, Kiefer- und Gaumenspalten am Behandlungszentrum des Universitätsspital Basels. 2019. Doctorate Dental Medicine, Esad Can, University of Basel. Supervised-student-publication by Mueller AAhttps://edoc.unibas.ch/81338/
     
  32. Naudot M, Barre A, Caula A, Sevestre H, Dakpé S, Mueller AA, Devauchelle B, Testelin S, Marolleau JP, Le Ricousse S. Co-transplantation of Wharton’s jelly mesenchymal stem cell-derived osteoblasts with differentiated endothelial cells does not stimulate blood vessel and osteoid formation in nude mice models. J Tissue Eng Regen Med. 2019;14(2):257-271. https://doi.org/10.1002/term.2989
     
  33. Walter C, Müller AA, Schmidt JC. Hirnabszess als lebensbedrohliche Komplikation einer unbehandelten schweren Parodontitis ? Parodontologie. 2019;30(4):367-386. https://www.quintessence-publishing.com/deu/de/article/835566/parodontologie/2019/04/hirnabszess-als-lebensbedrohliche-komplikation-einer-unbehandelten-schweren-parodontitis
     
  34. Ducret M, Farges J-C, Pasdeloup M, Perrier-Groult E, Mueller AA, Mallein-Gerin F and Fabre H. Phenotypic Identification of Dental Pulp Mesenchymal Stem/Stromal Cells Subpopulations with Multiparametric Flow Cytometry. Odontogenesis Methods Protoc Methods Mol Biol. 2019;1922(January):77-90. doi.org/10.1007/978-1-4939-9012-2_8
     
  35. Beiglboeck F, Thieringer FM, Scherrer G, Mueller AA. 3D-printing for orthopedic treatment of infants with cleft lips and palate deformities. Int J Oral Maxillofac Surg. 2019;48:5. https://doi.org/10.1016/j.ijom.2019.03.583
     
  36. Nalabothu P, Dalstra M, Zeilhofer HF, Mueller AA, Verna C. Biomechanical analysis of mucoperiosteal tissue strains during treatment of cleft palate defects. 288 European Journal of Orthodontics. 2019;41(5). https://academic.oup.com/ejo/article/41/5/e1/5572373
     
  37. Kansy K, Mueller AA, Mücke T, Koersgen F, Wolff KD, Zeilhofer HF, Hölzle F, Pradel W, Schneider M, Kolk A, Smeets R, Acero J, Haers P, Ghali GE and Hoffmann J. A worldwide comparison of the management of surgical treatment of advanced oral cancer. J Cranio-Maxillofacial Surg. 2018;46(3):511-520. https://doi.org/10.1016/j.jcms.2017.12.031
     
  38. Kansy K, Mueller AA, Mücke T, Koersgen F, Wolff KD, Zeilhofer HF, Hölzle F, Pradel W, Schneider M, Kolk A, Smeets R, Acero J, Haers P, Ghali GE and Hoffmann J. A worldwide comparison of the management of T1 and T2 anterior floor of the mouth and tongue squamous cell carcinoma – Extent of surgical resection and reconstructive measures. J Cranio-Maxillofacial Surg. 2017;45(12):2097-2104. https://doi.org/10.1016/j.jcms.2017.09.012
     
  39. Berg B-I, Mueller AA, Augello M, Berg S, Jaquiéry C. Imaging in Patients with Bisphosphonate-Associated Osteonecrosis of the Jaws (MRONJ). Dent J. 2016;4(3):29. https://doi.org/10.3390/dj4030029
     
  40. Brand S, Zimmerer S, Kalak N, Von Planta S, Schwenzer-Zimmerer K, Mueller AA, Zeilhofer HF, Holsboer-Trachsler E. Compared to controls, patients with ruptured aneurysm and surgical intervention show increase in symptoms of depression and lower cognitive performance, but their objective sleep is not affected. World J Biol Psychiatry. 2015;16(2):96-105. 
    https://doi.org/10.3109/15622975.2014.888093
     
  41. Kansy K, Mueller AA, Mücke T, Koersgen F, Wolff KD, Zeilhofer HF, Hölzle F, Pradel W, Schneider M, Kolk A, Smeets R, Acero J, Haers P, Ghali GE and Hoffmann J. Microsurgical reconstruction of the head and neck region: Current concepts of maxillofacial surgery units worldwide. J Cranio-Maxillofacial Surg. 2015;43(8):1364-1368. https://doi.org/10.1016/j.jcms.2015.06.034
     
  42. Vajgel A, Santos TDS, Camargo IB, De Oliveira DM, Laureano Filho JR, De Holanda Vasconcellos RJ, Lima SM, Pereira Filho VA, Mueller AA and Juergens P. Treatment of condylar fractures with an intraoral approach using an angulated screwdriver: Results of a multicentre study. J Cranio-Maxillofacial Surg. 2015;43(1):34-42. https://doi.org/10.1016/j.jcms.2014.10.006
     
  43. Augello M, Berg B-I, Mueller AA, Schwenzer-Zimmerer K. Two case reports with literature review of the EEC syndrome: Clinical presentation and management. Case Reports in Plastic Surgery and Hand Surgery. 2015; 2(3-4):63-66. https://doi.org/10.3109/23320885.2015.1086273
     
  44. Mueller AA, Neue Verfahren zur Wiederherstellung kiefer-gesichtschirurgischer Defekte, insbesondere bei Lippen-Kiefer-Gaumenspalten und nach Tumorresektionen. 2015, Postdoctoral Thesis, University of Basel, Faculty of Medicine. https://edoc.unibas.ch/80509/
     
  45. Kansy K, Mueller AA, Mücke T, Kopp J-P, Koersgen F, Wolff KD, Zeilhofer H-F, Hölzle F, Pradel W, Schneider M, Kolk A, Smeets R, Acero J, Hoffmann J,D€OSAK Collaborative Group for Microsurgical Reconstruction. Microsurgical reconstruction of the head and neck - Current concepts of maxillofacial surgery in Europe. J Cranio-Maxillofacial Surg. 2014;42(8):1610-1613. https://doi.org/10.1016/j.jcms.2014.04.030
     
  46. Mueller AA, Kalak N, Schwenzer-Zimmerer K, Holsboer-Trachsler E, Brand S. Cortisol levels and sleep patterns in infants with orofacial clefts undergoing surgery. Neuropsychiatr Dis Treat. 2014;10:1965-1972. https://doi.org/10.2147/NDT.S71785
     
  47. Mueller AA, Forraz N, Gueven S, Degoul GAO, Pagnon-Minot A, Hartmann D, Martin I, Scherberich A, McGuckin C. Osteoblastic differentiation of wharton jelly biopsy specimens and their mesenchymal stromal cells after serum-free culture. Plastic and Reconstructive Surgery. 2014; 134(1) 59e-69e. DOI: 10.1097/PRS.0000000000000305
     
  48. Mueller, AA. Complementing surgical with biomedical and engineering methods to evolve lip and nose reconstruction. 2013, Doctoral Thesis, University of Basel, Faculty of Medicine. http://edoc.unibas.ch/diss/DissB_10955
     
  49. Mueller AA, Zschokke I, Brand S, Hockenjos C, Zeilhofer HF, Schwenzer-Zimmerer K. One-stage cleft repair outcome at age 6- to 18-years - A comparison to the Eurocleft study data. Br J Oral Maxillofac Surg. 2012;50(8):762-768. dx.doi.org/10.1016/j.bjoms.2012.02.002
     
  50. Mueller AA, Schumann D, Reddy RR, Schwenzer-Zimmerer K, Mueller-Gerbl M, Zeilhofer HF, Sailer HF, Reddy SG. Intraoperative vascular anatomy, arterial blood flow velocity, and microcirculation in unilateral and bilateral cleft lip repair. Plast Reconstr Surg. 2012;130(5):1120-1130. doi:10.1097/PRS.0b013e318267d4fb
     
  51. Mücke T, Mueller AA, Kansy K, Hallermann W, Kerkmann H, Schuck N, Zeilhofer HF, Hoffmann J and Hölzle F. Microsurgical reconstruction of the head and neck-Current practice of maxillofacial units in Germany, Austria, and Switzerland. J Cranio-Maxillofacial Surg. 2011;39(6):449-452. https://doi.org/10.1016/j.jcms.2010.10.019
     
  52. Mueller AA, Paysan P, Schumacher R, et al. Missing facial parts computed by a morphable model and transferred directly to a polyamide laser-sintered prosthesis: An innovation study. Br J Oral Maxillofac Surg. 2011;49(8):e67-e71. https://doi.org/10.1016/j.bjoms.2011.02.00
     
  53. Zimmerer SME, Conen A, Mueller AA, Sailer M, Taub E, Flückiger U, Schwenzer-Zimmerer KC. Spinal epidural abscess: Aetiology, predisponent factors and clinical outcomes in a 4-year prospective study. European Spine Journal. 2011;20(12):2228-2234. DOI: 10.1007/s00586-011-1838-y
     
  54. Brand S, Mueller AAQuality of life among children, adolescents and adults with orofacial clefts. In: JH Stone, M Blouin, editors. International Encyclopedia of Rehabilitation. University of Buffalo. 2010.
     
  55. Mueller AA, Saldamli B, Stübinger S, Walter C, Flückiger U, Merlo A, Schwenzer-Zimmerer K, Zeilhofer HF and Zimmerer S. Oral bacterial cultures in nontraumatic brain abscesses: results of a first-line study. Oral Surgery, Oral Med Oral Pathol Oral Radiol Endodontology. 2009;107(4):469-476. https://doi.org/10.1016/j.tripleo.2008.09.035
     
  56. Brand S, Blechschmidt A, Mueller AA, Sader R, Schwenzer-Zimmerer K, Zeilhofer HF and Holsboer-Trachsler E. Psychosocial functioning and sleep patterns in children and adolescents with cleft lip and palate (CLP) compared with healthy controls. Cleft Palate-Craniofacial J. 2009;46(2):124-135. https://doi.org/10.1597/07-165.1
     
  57. Schwenzer-Zimmerer K, Boerner BI, Schwenzer NF, Mueller AA, Juergens P, Ringenbach A, Schkommodau E and Zeilhofer HF. Facial acquisition by dynamic optical tracked laser imaging: a new approach. J Plast Reconstr Aesthetic Surg. 2009;62(9):1181-1186. https://doi.org/10.1016/j.bjps.2007.11.080
     
  58. Kober C, Berg BI, Mueller AA, Juergens P, Zeilhofer HF, Zimmerer S, Schwenzer-Zimmerer K. Multimodal visualization of craniofacial tumors of large dimensions. World Congress on Medical Physics and Biomedical Engineering 2009;25(4):1616-1619. https://link.springer.com/chapter/10.1007/978-3-642-03882-2_428
     
  59. Juergens PC, Buitrago-Tellez C, Mueller AA, Kunz C, Schwenzer-Zimmerer K, Zeilhofer HF. Preoperative planning and perioperative management for the surgical treatment of a huge vascular malformation with infiltration of the maxilla. Int J Oral Maxillofac Surg. 2009;38:5. doi.org/10.1016/j.ijom.2009.03.472
     
  60. Juergens P, Kim H, Kunz C, Beinemann J, Mueller AA, Schwenzer-Zimmerer K, Zeilhofer HF. Intraoperative three-dimensional real-time navigation in orthognathic surgery. Int J Oral Maxillofac Surg. 2009;38:5(474) https://doi.org/10.1016/j.ijom.2009.03.276
     
  61. Brand S, Mueller AA, Schwenzer-Zimmerer K, Sader R, Zeilhofer HF, Holsboer-Trachsler E. The impact of mother's behavior on infant's sleep before and after surgical intervention for cleft-lip-palate (CLP) repair. Archives of Disease in Childhood 2008;93(2):225. https://adc.bmj.com/content/93/Suppl_2/ps225.abstract
     
  62. Mueller AA, Paysan P, Schumacher R, Berg-Boerner B-I, Maurer J, Schkommodau E, Vetter T, Zeilhofer H-F, Schwenzer-Zimmerer K. Facial reconstruction using an individualized 3D technique-Directly from surface scanning to facial prosthesis. Onkologie 2008;31.
     
  63. Schwenzer-Zimmerer K, Boerner B-I, Mueller AA, Jürgens P, Ringenbach A, Schkommodau E. T-Scan: First Experiences with Acquisition of Cleft Morphology. Adv Med Eng. Published online 2007:458-463. doi.org/10.1007/978-3-540-68764-1_77
     
  64. Juergens PC, Mueller AA, Zimmerer S, Kunz C, Zeilhofer HF, Schwenzer-Zimmerer K. Implementation of 3D-planning and navigation tools in the clinical routine for the correction of craniofacial deformities. Int J Oral Maxillofac Surg. 2007;36:11. https://doi.org/10.1016/j.ijom.2007.08.132
     
  65. Mueller AA, Sader R, Honigmann K, Zeilhofer HF and Schwenzer-Zimmerer K. Central nervous malformations in presence of clefts reflect developmental interplay. Int J Oral Maxillofac Surg. 2007;36(4):289-295. https://doi.org/10.1016/j.ijom.2006.10.018
     
  66. Leiggener CS, Curtis R, Mueller AA, Pfluger D, Gogolewski S and Rahn BA. Influence of copolymer composition of polylactide implants on cranial bone regeneration. Biomaterials. 2006;27(2):202-207. https://doi.org/10.1016/j.biomaterials.2005.05.068
     
  67. Zimmerer S, Saldamli B, Mueller AA, Stübinger S, Schwenzer K. Odontogenious cerebral abscess-Report of 7 cases. Journal of Cranio-Maxillo-Facial Surgery, 2006;34(S1):46 https://doi.org/10.1016/S1010-5182(06)60191-1
     
  68. Mueller AA, Rahn BA, Gogolewski S and Leiggener CS. Early dural reaction to polylactide in cranial defects in rabbits. Pediatr Neurosurg. 2005;41(6):285-291. https://doi.org/10.1159/000088730
     
  69. Mueller AA, Early dural reaction to polylactide in cranial defects of rabbits. 2004, Doctoral Thesis, University of Basel, Faculty of Medicine. https://edoc.unibas.ch/80507/
     
  70. Mueller AA, Epidemiologie von Begleitmissbildungen bei Lippen- und Gaumenspalten. 2001, Doctoral Thesis, University of Basel, Faculty of Medicine. https://edoc.unibas.ch/80508/